The golden poison frog (Phyllobates terribilis) of Colombia carries enough batrachotoxin in its skin — roughly 1 milligram — to be lethal to an estimated 10 to 20 adult humans (or up to 10,000 mice) if it entered the bloodstream, the highest potency-to-body-size ratio of any known animal toxin. Indigenous Emberá people historically used its secretions to poison blowgun darts.
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The golden poison frog (Phyllobates terribilis) of Colombia carries enough batrachotoxin in its skin — roughly 1 milligram — to be lethal to an estimated 10 to 20 adult humans (or up to 10,000 mice) if it entered the bloodstream, the highest potency-to-body-size ratio of any known animal toxin. Indigenous Emberá people historically used its secretions to poison blowgun darts.
The greatest estimated number of adult human lethal doses carried in the toxin reserve of a single individual animal.
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Permanent ID limitsregistry.com/limits/LR-GOLDEN-POISON-FROG-MOST-TOXIC
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Limits Registry. LR-GOLDEN-POISON-FROG-MOST-TOXIC. Most toxic animal, by lethal dose per body weight. 2026.