Limits RegistryPUBLIC RECORDLimits RegistryPUBLIC RECORDLimits RegistryPUBLIC RECORDLimits RegistryXPRIZE Healthspan is a $101M competition (launched 2023, running through 2030) challenging teams to develop a real therapeutic — not just a way to slow aging, but to measurably reverse already-occurred functional decline. As of August 2026, 20 finalist teams are in clinical trials; 10 received $1M Milestone 2 awards, but no grand prize has been claimed.
The question, scope, and sources behind this Registry record.
Using a treatment protocol of one year or less, restore muscle, cognitive, and immune function in adults aged 50-80 by a minimum of 10 years, with a stated goal of 20 years, relative to each participant's pre-treatment baseline.
Change a parameter to stress-test whether a proposed result is still inside the published specification. This is an audit aid, not a proof checker.
This record has no editable parameters. Read the formal question and assumptions before challenging it.
Current frontiers derived from accepted Claims.
The frontier is not sacred
Most progress starts with a disagreement that survives contact with evidence. If you can push the known lower bound up or pull the upper bound down, show us the work.
≥ when you have shown that at least this value is achievable.≤ when you have shown that anything above this value is impossible.No vibes. State the value, define the scope, and link the paper, proof, code, or reproduction that lets another person check it. Editors review every challenge before the public record changes.
Challenge this recordAssertions tied to evidence, attribution, and review.
No accepted Claims are recorded for this Limit yet.
The frontier as it changed over time.
Only accepted Claims matching the current specification contribute to the displayed bounds. Strict inequalities remain open; contradictory Claims require editorial review.