The Carter Center reported only 10 human Guinea worm cases worldwide in 2025 — 4 in Chad, 4 in Ethiopia and 2 in South Sudan — the lowest ever and down from 15 in 2024. When the eradication campaign began in 1986 there were about 3.5 million cases a year in 21 countries; it would be the second human disease eradicated, and the first without a vaccine or medicine.
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The Carter Center reported only 10 human Guinea worm cases worldwide in 2025 — 4 in Chad, 4 in Ethiopia and 2 in South Sudan — the lowest ever and down from 15 in 2024. When the eradication campaign began in 1986 there were about 3.5 million cases a year in 21 countries; it would be the second human disease eradicated, and the first without a vaccine or medicine.
The lowest annual worldwide count of human dracunculiasis (Guinea worm disease) cases reported by the global eradication programme.
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Permanent ID limitsregistry.com/limits/LR-LOWEST-ANNUAL-GUINEA-WORM-CASES
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Limits Registry. LR-LOWEST-ANNUAL-GUINEA-WORM-CASES. Fewest human Guinea worm cases reported in a year. 2026.