Limits RegistryPUBLIC RECORD
Limits RegistryMaitotoxin, a marine toxin from dinoflagellates with a molecular weight of about 3,400 g/mol and over 100 stereocenters, was declared totally synthesized by the Kishi group at Harvard in 2019 after a project spanning more than three decades — widely regarded as the most complex non-polymeric molecule ever chemically synthesized.
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Maitotoxin, a marine toxin from dinoflagellates with a molecular weight of about 3,400 g/mol and over 100 stereocenters, was declared totally synthesized by the Kishi group at Harvard in 2019 after a project spanning more than three decades — widely regarded as the most complex non-polymeric molecule ever chemically synthesized.
The highest molecular weight achieved by chemists in the total synthesis (fully lab-built from simple starting materials, as opposed to biological extraction) of a single defined natural product molecule.
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1 accepted Claim, with 1 linked evidence records.
Permanent ID limitsregistry.com/limits/LR-LARGEST-SYNTHETIC-MOLECULE-BY-MASS
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Limits Registry. LR-LARGEST-SYNTHETIC-MOLECULE-BY-MASS. Largest fully synthetic small molecule by molecular weight. 2026.