Limits RegistryPUBLIC RECORD
Limits RegistryIn 1972, Robert Burns Woodward at Harvard and Albert Eschenmoser at ETH Zürich completed the total synthesis of vitamin B12 after an 11-year collaboration involving about 100 postdoctoral researchers. Long regarded as a landmark of organic synthesis, the project also inspired the Woodward–Hoffmann rules on orbital symmetry.
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In 1972, Robert Burns Woodward at Harvard and Albert Eschenmoser at ETH Zürich completed the total synthesis of vitamin B12 after an 11-year collaboration involving about 100 postdoctoral researchers. Long regarded as a landmark of organic synthesis, the project also inspired the Woodward–Hoffmann rules on orbital symmetry.
The year in which the total chemical synthesis of vitamin B12 (cyanocobalamin) from simple precursors was completed.
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Limits Registry. LR-FIRST-TOTAL-SYNTHESIS-VITAMIN-B12. First total synthesis of vitamin B12. 2026.