On 19 March 1987, the US FDA approved zidovudine (AZT, Retrovir, Burroughs Wellcome), a nucleoside reverse-transcriptase inhibitor, for the treatment of HIV/AIDS after one of the fastest reviews in FDA history. AZT was first synthesised in 1964 as a potential cancer drug; its anti-HIV activity was shown at the US National Cancer Institute in 1985.
The question, scope, and sources behind this Registry record.
On 19 March 1987, the US FDA approved zidovudine (AZT, Retrovir, Burroughs Wellcome), a nucleoside reverse-transcriptase inhibitor, for the treatment of HIV/AIDS after one of the fastest reviews in FDA history. AZT was first synthesised in 1964 as a potential cancer drug; its anti-HIV activity was shown at the US National Cancer Institute in 1985.
The year in which a drug regulator first approved a medicine that directly inhibits HIV replication.
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Current frontiers derived from accepted Claims.
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The frontier as it changed over time.
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1 accepted Claim, with 1 linked evidence records.
Permanent ID limitsregistry.com/limits/LR-FIRST-HIV-ANTIRETROVIRAL-APPROVED
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Limits Registry. LR-FIRST-HIV-ANTIRETROVIRAL-APPROVED. First antiretroviral drug approved for HIV. 2026.