Limits RegistryPUBLIC RECORD
Limits RegistryOn 27 August 1942, Yale pharmacologists Louis Goodman and Alfred Gilman, with surgeon Gustaf Lindskog, gave intravenous nitrogen mustard to a patient with advanced lymphosarcoma (known as J.D.), producing a dramatic though temporary tumour regression. The work, kept secret during the war, was published in 1946, and the drug (mustine) became the first approved chemotherapy agent.
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On 27 August 1942, Yale pharmacologists Louis Goodman and Alfred Gilman, with surgeon Gustaf Lindskog, gave intravenous nitrogen mustard to a patient with advanced lymphosarcoma (known as J.D.), producing a dramatic though temporary tumour regression. The work, kept secret during the war, was published in 1946, and the drug (mustine) became the first approved chemotherapy agent.
The year in which a cancer patient was first treated with a systemic cytotoxic chemical agent designed to kill tumour cells, marking the start of modern chemotherapy.
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Permanent ID limitsregistry.com/limits/LR-FIRST-CANCER-CHEMOTHERAPY-PATIENT
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Limits Registry. LR-FIRST-CANCER-CHEMOTHERAPY-PATIENT. First patient treated with modern cancer chemotherapy. 2026.